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The MHICC is now Seriant !
The Montreal Health Innovations Coordinating Center (MHICC) is now Seriant.
Our new name reflects a bold step forward— expanding beyond cardiology and embracing innovations in clinical trials with a global reach.
While our identity has evolved, our commitment to operational excellence, client satisfaction, and quality remains the same.
The Value of Pragmatic Randomized Clinical Trials: Strategic Approaches
December 9, 2025
Discover how pragmatic clinical trials combine scientific rigor with operational flexibility through trial design and execution, empowering sponsors to reduce trial risk and enhance real-world applicability. Learn from leading experts how pragmatic clinical trial models can support decision-making—in the clinic and beyond—in today’s competitive environment.
SPEAKERS
Dr. Guillaume Marquis-Gravel, MD, MSc
Interventional Cardiologist | Associate Professor of Clinics
Montreal Heart Institute | Université de Montréal
Dr. Guillaume Marquis-Gravel is an interventional cardiologist at the Montreal Heart Institute and Associate Professor of Clinics at the Université de Montréal. Trained at Duke University in interventional cardiology and clinical research, his work focuses on antithrombotic therapies, coronary artery disease, and revascularization. He has led and contributed to pragmatic trials including ADAPTABLE, NEPTUNE, and PANTHEON, authored over 120 publications, and co-chaired the 2023 Canadian antiplatelet therapy guidelines.
Melissa Stremel, BA&Sc
Director of Operations | Seriant
Melissa Stremel has over 20 years of experience leading global clinical trial operations across all phases (I–IV) and diverse therapeutic areas. Known for her strategic vision and collaborative approach, she has contributed to the approval of numerous treatments in neurology, psychiatry, rare and infectious diseases. At Seriant, she drives innovation in clinical research, advancing trials to deliver tailored strategies for complex, multinational studies.
